Type the MCV from your blood count — the average size of your red blood cells, printed in fL. You see it against the 80–100 fL range MedlinePlus’s blood count page and StatPearls print, and the 79–95 fL MedlinePlus’s newer RBC indices page prints, with what the sources say a small or large result may point to. Your lab’s own range, and your doctor, have the last word.
88 fL is
Inside the 80–100 fL range red cells of the size the range expects
88 fL: inside the 80–100 fL range (MedlinePlus’s blood count page, StatPearls), and inside the 79–95 fL on MedlinePlus’s newer RBC indices page.
That is inside the range. The range printed on your own lab report is the one your doctor will read it against, with your other results.
MedlinePlus: anemia with a normal MCV may happen with
- A sudden loss of blood
- Kidney failure
- Aplastic anemia (uncommon)
In the sources’ words
- It’s also possible to have anemia with a normal MCV.
- MCV normal. Normocytic anemia (may be due to sudden blood loss, long-term diseases, kidney failure, aplastic anemia, or human-made heart valves).
The number read beside it
- Hemoglobin Level Checker — MedlinePlus: “It’s also possible to have anemia with a normal MCV.”
| Source | Under | Range | Above |
|---|---|---|---|
| MedlinePlus, blood count page (2024) | under 80 fL | 80–100 fL | over 100 fL |
| StatPearls (2024) | below 80 fL | 80–100 fL | exceeding 100 fL |
| MedlinePlus, RBC indices page (2026) | under 79 fL | 79–95 fL | over 95 fL |
What an MCV can and cannot tell you. MedlinePlus: “An MCV test alone cannot diagnose any disease.” “If your MCV levels are not in the normal range, it doesn’t always mean you have a medical problem that needs treatment. Your age, diet, activity level, medicines, menstrual period, and other conditions can affect the test results.”
This is not medical advice and it does not diagnose anything. It shows where a number sits against published ranges; what your result means for you depends on your lab, your other results, your history and your doctor.
MedlinePlus’s blood count page prints “MCV: 80 to 100 femtoliter”, and StatPearls agrees: “a normal MCV ranges between 80 and 100 fL”, with under 80 called small and over 100 large. MedlinePlus’s newer RBC indices page prints 79 to 95 fL. Among the reasons MedlinePlus lists, a small MCV can point towards iron, and a large one towards vitamin B12 or folate.
How to use it
Find “MCV” (or “Mean corpuscular volume”) on your complete blood count and type the number — it is printed in fL, femtoliters, and usually looks like 88. You see where it sits against the 80–100 fL range and against MedlinePlus’s newer 79–95 fL, what MedlinePlus says a small, normal or large result may be a sign of, and the number your doctor will read beside it. Where the two ranges disagree, the page says so instead of choosing. If the number you typed is in the 20s or 30s and printed in pg or g/dL, it is the MCH or MCHC line, not the MCV — the page tells you.
What MCV measures, and the ranges
MedlinePlus: “MCV stands for mean corpuscular volume. An MCV blood test measures the average size of your red blood cells.” MedlinePlus’s blood count page lists it among the measurements a CBC provides, and its RBC indices page says the indices “are usually used to help diagnose the cause of anemia, a condition in which there are too few red blood cells”.
The ranges are not all the same. MedlinePlus’s Complete blood count page (review date 10/14/2024) prints “MCV: 80 to 100 femtoliter”. StatPearls’ chapter on Mean Corpuscular Volume (last update July 27, 2024): “On a complete blood count (CBC), the MCV measure is below 80 fL, whereas a normal MCV ranges between 80 and 100 fL.” and “Macrocytic anemia is characterized by an increased average RBC volume compared to normal levels, with an MCV measurement exceeding 100 fL on a CBC.” MedlinePlus’s RBC indices page (review date 2/27/2026) prints “MCV: 79 to 95 femtoliter”, and adds: “Normal value ranges may vary slightly among different labs.” Neither MedlinePlus page prints a range by age or sex, so this page does not invent one — for a child, the child’s report is the range.
How the number is made, in StatPearls’ words: “To calculate the MCV, the percent hematocrit is divided by the erythrocyte count, and the result is multiplied by 10”. So a report with a hematocrit and a red cell count already holds its MCV:
| Hematocrit | Red cell count (million/mcL) | MCV |
|---|---|---|
| 42% | 4.7 | 89.4 fL |
| 36% | 4.8 | 75 fL |
| 45% | 4.2 | 107.1 fL |
| MCV | 80–100 fL (MedlinePlus blood count, StatPearls) | 79–95 fL (MedlinePlus RBC indices) |
|---|---|---|
| 72 fL | Under | Under |
| 79.5 fL | Under | Inside |
| 85 fL | Inside | Inside |
| 92 fL | Inside | Inside |
| 97 fL | Inside | Above |
| 102 fL | Above | Above |
| 110 fL | Above | Above |
What a small or large MCV may point to
MedlinePlus’s MCV test page (last updated December 2, 2024) is careful first: “An MCV test alone cannot diagnose any disease.” Then: if your red blood cells are smaller than normal, it may be a sign of “Certain types of anemia, including iron deficiency anemia, the most common form of anemia. It happens when you don’t have enough iron in your body.” or “Thalassemia, which is a group of blood disorders that are inherited (passed down through families).” If they are larger than normal: “Pernicious anemia, which may be caused by: A lack of vitamin B12; A disease that affects your body’s ability to use vitamin B12, such as certain autoimmune diseases, celiac disease, or Crohn’s disease”; “Anemia caused by a lack of folic acid”; “Liver disease”. And “It’s also possible to have anemia with a normal MCV.” — after “A sudden loss of blood”, “Kidney failure” or “Aplastic anemia (uncommon)”.
The RBC indices page puts it in one line each: “MCV below normal. Microcytic anemia (may be due to low iron levels, lead poisoning, or thalassemia).” “MCV normal. Normocytic anemia (may be due to sudden blood loss, long-term diseases, kidney failure, aplastic anemia, or human-made heart valves).” “MCV above normal. Macrocytic anemia (may be due to low folate or vitamin B12 levels, or chemotherapy) or liver disease.” StatPearls adds that “non-megaloblastic anemia can result from hepatic insufficiency, chronic alcoholism, or a rare congenital disease known as Diamond-Blackfan anemia”.
The NIH’s Office of Dietary Supplements says the same from the nutrient side. On iron: “IDA is characterized by low hemoglobin concentrations and decreases in hematocrit (the proportion of red blood cells in blood by volume) and mean corpuscular volume (a measure of erythrocyte size)”, and “the resulting microcytic, hypochromic anemia is characterized by small red blood cells with low hemoglobin concentrations”. On folate: “Megaloblastic anemia, which is characterized by large, abnormally nucleated erythrocytes, is the primary clinical sign of folate or vitamin B12 deficiency”. On vitamin B12: “the hallmark megaloblastic anemia (characterized by large, abnormally nucleated red blood cells)”. Which of these, if any, applies to you is your doctor’s question, read with your other results — not a list’s.
Worked examples
- 88 fL (the page’s example) is inside both ranges.
- 76 fL is under both: red cells smaller than the range. The number ODS calls “the most efficient and cost-effective test for diagnosing iron deficiency” is serum ferritin — see the Ferritin Level Checker.
- 97 fL is inside 80–100 but above MedlinePlus’s newer 79–95 — where the two disagree, and the page says so.
- 104 fL is above both: red cells larger than the range. The Vitamin B12 Level Checker reads the vitamin ODS ties to large red cells.
Common mistakes
- Reading the MCV on its own. MedlinePlus: “An MCV test alone cannot diagnose any disease.” Your doctor reads it with your hemoglobin and hematocrit.
- Starting iron or vitamin B12 because of the MCV alone. A small MCV has more than one cause (thalassemia is inherited, not a shortage), and so does a large one; the tests your doctor orders next decide which.
- Taking a lot of folic acid and reading a normal MCV as “my B12 is fine”. NIH ODS: “Large amounts of folate can correct the megaloblastic anemia, but not the neurological damage, that can result from vitamin B12 deficiency.”
- Copying the wrong line. MCH (picograms) and MCHC (g/dL) sit just under MCV on the report; MedlinePlus prints “MCH: 26 to 33 picograms/cell (female); 27 to 33 picograms/cell (male)” and “MCHC: 32 to 36 grams hemoglobin/deciliter (g/dL) or 320 to 360 grams hemoglobin per liter (g/L)”.
Frequently asked questions
What is an MCV blood test?
A measure of the average size of your red blood cells, in femtoliters (fL). MedlinePlus: “An MCV blood test is often part of a complete blood count (CBC), a group of tests that measures the number and type of cells in your blood.” It is used to help find the cause of anemia.
What is the MCV normal range?
80 to 100 fL on MedlinePlus’s blood count page and in StatPearls; 79 to 95 fL on MedlinePlus’s newer RBC indices page. Labs set their own ranges, and the one printed on your report is the one your doctor uses.
What does a low MCV mean?
That your red cells are smaller than the range expects — StatPearls draws that line below 80 fL. MedlinePlus lists iron deficiency anemia, “the most common form of anemia”, and thalassemia among what it may be a sign of. It is a conversation with your doctor, not a diagnosis.
What does a high MCV mean?
That your red cells are larger than the range expects — StatPearls draws that line above 100 fL. MedlinePlus lists a lack of vitamin B12, a lack of folic acid and liver disease; StatPearls adds chronic alcoholism among the causes of large cells without megaloblastic changes.
Can you have anemia with a normal MCV?
Yes. MedlinePlus: “It’s also possible to have anemia with a normal MCV.” It names sudden blood loss, kidney failure and aplastic anemia. StatPearls: “Normocytic anemia has a low hemoglobin and hematocrit range, but MCV is in the normal range of 80 to 100 fL.”
Can folic acid supplements change my MCV?
The NIH Office of Dietary Supplements: “Large amounts of folate can correct the megaloblastic anemia, but not the neurological damage, that can result from vitamin B12 deficiency.” That is why a normal MCV in someone taking a lot of folic acid does not settle the B12 question.
Is MCV the same as MCH or MCHC?
No. MCV is the cells’ average size (fL); MCH is the hemoglobin per cell (pg); MCHC is the hemoglobin relative to the cell’s size (g/dL). MedlinePlus prints all three on its RBC indices page.
Read next
- How to Get Rid of Anemia? Best 4 Products
- Vitamin B12 as a Nootropic
- Vitamin B9
- Folic acid for Women & Men
This is not medical advice, and nothing here diagnoses or treats anything. It shows where a number sits against published ranges; what it means for you is a conversation with your doctor, who knows your lab, your other results and your history. Some links on this site are affiliate links: I buy what I review at full price, and a commission never changes a verdict.